Watched A Video And It Got Me Curious On This Study

Any thoughts on this study?

Vaping may disrupt immune cells in the lungs, mouse study finds

If I understood correctly, despite mentioning the THC issue, they are also trying to imply that regular, legal vaping may be the culprit for many of the lung illnesses that have came up recently.  


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New Study About Vaping

Hopefully the link will work now lol

New Study: Adults Who Vape Flavoured E-Cigs Have More Smoking Cessation Success %  

Major Anti-vaping Scientific Study Retracted

"
Vaping is supposed to be a form of harm reduction, that is, allow nicotine addicts to have access to the drug without the harmful tars and chemicals in cigarettes that cause cancer, heart disease, and other maladies.

Last year, the Journal of the American Heart Association published a study finding that vaping posed as great a heart risk as smoking itself. That study fueled public policies at all levels of government to stifle the industry. A lot of small business people had their livelihoods destroyed or damaged as a result.

Now, the study has been retracted — which is a very big deal in science — because the editors are “concerned that the study conclusion is unreliable” due to what appears to have been an uncompleted peer review process..........."

Major Anti-Vaping Scientific Study Retracted | National Review


Score one for our side. 'They will not stop until tobacco becomes regulated like a hard drug - 'We will not stop until our rights, especially our right to use a less harmful form of tobacco, such as vaping,
is assured.  

A Study, Dangers Of Vaping

I know this might piss some people off, but a fair study was done, and found that on high voltage tanks and MOD's produce high levels of formaldehyde

nytimes.
com/2014/05/04/business/some-e-cigarettes-deliver-a-puff-of-carcinogens.html?smid=fb-share  

Nicotine Absorption From Juul, New Study

First published study showing that Juul can deliver a higher and faster boost in blood nicotine than most other e-cigarettes and similar to a cigarette. Nicotine Absorption Profile Among Pod-Based Electronic Nicotine Delivery System Users Any thoughts?  

At Least They Aren't Vaping

Alcohol beverage companies made estimated $17.5 billion on underage drinking, study says
By Sandee LaMotte, CNN 4 hrs ago

An estimated $17.5 billion of beer and liquor sales in the United States in 2016 was consumed by minors, with the products of three companies -- AB InBev, Molson Coors Beverage Co. and Diageo -- accounting for nearly 45% of underage youth consumption, a new study found.  

Vaping Ad Tactics 'exploited' The Pandemic, Study Says

Vaping ad tactics 'exploited' the pandemic, study says - CNN  

New 'baddie'. Mint/ Menthol Flavor Causes Cancer.

E-cigarette cancer warning as new study finds mint and menthol flavour risk

The study of menthol and peppermint vapes revealed high concentrations of a carcinogenic additive called pulegone that US watchdogs recently banned in food.

The pulegone additive, a constituent of oil extracts from mint plants, is believed to cause liver cancer if absorbed in high enough quantities.​

Mint, menthol e-cigarette liquids high in cancer-causing compound: study - Reuters

The findings, published in the journal JAMA Internal Medicine​

Vape Pods Taste Minty Thanks to Extremely High Levels of a Chemical Banned in Food

But despite all the evidence that pulegone is carcinogenic and causes liver toxicity, researchers found the chemical is present in mint and menthol-flavored e-cig liquid at levels far above a safe threshold.​

This study is the latest in a growing pile of proof to how little-regulated e-cigs and vapes are. To illustrate that, researchers compared pulegone levels in mint and menthol e-cig liquid to levels in menthol cigarettes. At all levels of daily consumption, pulegone exposure from vape pods are significantly higher than exposure from cigarettes, with rates ranging from 44 to 1,608 times higher.​

So much for Juul's best seller - menthol.  

Dr. F. Responds To A New Study (help With The Math)

So there was a cell study published recently that took human and rat lung cells and exposed them to both cigarette smoke and e-cig vapor (with and without nicotine). Dr. Farsilinos responded saying that the study was bogus based on a detail he saw in one of the charts.

What happened is they were measuring the nicotine in molarity and not in milliliters. For those of you unfamiliar, 1M = 1 molar of solute in 1 liter of a solution. So, essentially 1 molar (1M) = 1 mol/L.

Dr F. concluded that they were using concentrations of nicotine that would never been seen in real life conditions (see the link above where he explains).

Dr. F's detraction resulted from a chart that listed the following concentrations of nicotine they applied to the cells. They we

.1 mM
.5 mM
2.5 mM
5 mM
10 mM

(A mM = millimole or 1/1000th of a mole).

Now, the molar mass of nicotine is 162.23g/mol. This means that 1M of nicotine = 162.23g. Since 1M = 1mol/liter, this means that there would be 162.23g of nicotine in one liter of their solution.

Now here's where I am wondering if Dr. F messed up his calculation. A millimole = .001 M. Thus a millimole of nicotine = .16223g (let's round to .16g). That would be .16g/L.

Now .1 mM of nicotine = 160g x 0.0001 = .016g/L. And so on for the rest of the chart presented in the paper. Here would be the conversions in grams per liter:

.5 = .08g/L
2.5 = .4g/L
5 = .8g/L
10 = 1.6g/L

Now, you are probably thinking, "Yes, but you have grams per liter. We need milligrams per milliliter. Therefore, you would need to move the decimal three places to the right. Hence, .016g/L would equal 16mg/mL. Right?"

Wrong. 0.016g/L = 0.016mg/mL. It's the same. It's something we learn in elementary school called cancellation.

The density of pure nicotine is 1.01g/cm^3. This equates 1:1 with mg/mL. Thus, the density of pure nicotine (undiluted) would be 1.01g/mL or 1010mg/mL.

Dr. F, is claiming that 10 mM =1600mg/mL. This is impossible as that is more nicotine than is possible to fit into one mL, even if it was pure and undiluted. (As I said above, pure nicotine is 1010mg/mL).

I conclude that Dr. F. is wrong when he says they were using 16mg/mL, 80mg/mL, 400mg/mL, 800mg/mL, and especially 1600mg/mL (impossible), etc. He moved the decimal place over when he shouldn't have. Or perhaps I am completely wrong and talking out my behind (I am not a chemist and admit I could be totally confused about molarity and the densities and masses of the chemicals here).

I know we have chemists here. I would like it if an expert would show me the error of my ways, which I fully admit is possible. Again, I am no expert. I'm just a guy who thought that surely these researchers cannot be so silly as to use outrageous amounts of nicotine such as 1600mg/mL!  

Question About Cigarettes (vape Related)

So here lately with all the FDA stuff I've been seeing a lot about clean rooms & how sanitary different manufacturers juices are. I was just curious if anyone here knew how sanitary cigarette tobacco is, as in how well it's washed / handled / how often it's contaminated by misc. debris for comparison. I tried googling, but was only able to find legal doctrine. Would anyone happen to have a link to a study or similar to shed some light on the subject?  

Vaping And Running Vs Smoking And Running

So I started running again. I can say from experience that vaping has to be better for your lungs than smoking ! I was up to running 5 or more miles a day and up to 10 miles while smoking a pack a day. (I'm a former Marine so I tend to do things to the extreme.) When I was smoking in the beginning of a run I would feel a tightness in my chest and I used to attribute to having to get into an aerobic heartbeat. Breathing would be hard for a while. But I would always push myself to do the run. I would finish a run and stop and hack a bit then light a ciggarette. (..... I am lol) I always wondered how it would feel to run if I wasn't smoking. So I haven't run in quite some time (Old Man Winter) and I have been quit smoking for a while. So I started out with a short 2 mile run today. Guess what ? No tightness in the chest, no hard breathing and no hacking ! Can't wait to get back up into the big mile range again ! So if vaping actually had an effect on your lungs would I have not felt it ? In contrary vaping has greatly improved my lungs. So I don't need any scientific studies I just completed my own study ! Hey if anyone else has noticed the same thing let me know I'm interested in your opinion.