Acrolain? Following Article Claims Nicotine-free E-cigarette Vapor Also Damages Lung Cells!

So I've been mouth to lung vaping since I started vaping. Started at 24 mg with the Halo Triton and when I upgraded to the iStick and the Nautilus I lowered my nicotine down to 15 mg. It's been fine.......getting enough nicotine so I don't crave analogs, not getting too much nicotine so that I start feeling sick. Throat hit has been fine and not uncomfortable.

Yesterday I started doing lung hits with the iStick and the Nautilus and with the greater amount of vapor I can produce, I stepped the nicotine down to 12 mg since I also started to get a little lightheaded (I suppose with the greater amount of vapor I am also taking in more nicotine, even though nicotine absorption through the lungs is not supposed to be as good as through the mouth and nose). The juice that I am using is also a 70VG/30PG mix as compared to the 50/50 I was vaping before. However this morning I woke up with an irritated throat and the vape (even when switching back to mouth to lung) feels more harsh.

Do I need to step down the nicotine level even more to 6 mg? Is this normal when going from mouth to lung to direct lung hits? I'm not subohming, so I didn't expect that I would need to drop it down that much. I'm afraid that if I drop it down too much, then I'm going to have more cravings and will need to vape constantly.  

So I've heard a lot of people debating on this. Some say full mouth to lung, and hold it. Some say straight to lung and hold it.

Others say mouth to back of throat for the hit, then blow out slowly from the nose for the best absorption.


Is there any proven way to vape that gets the maximum nicotine? I always alternate but I'm curious to what everyone does/think.  

So there was a cell study published recently that took human and rat lung cells and exposed them to both cigarette smoke and e-cig vapor (with and without nicotine). Dr. Farsilinos responded saying that the study was bogus based on a detail he saw in one of the charts.

What happened is they were measuring the nicotine in molarity and not in milliliters. For those of you unfamiliar, 1M = 1 molar of solute in 1 liter of a solution. So, essentially 1 molar (1M) = 1 mol/L.

Dr F. concluded that they were using concentrations of nicotine that would never been seen in real life conditions (see the link above where he explains).

Dr. F's detraction resulted from a chart that listed the following concentrations of nicotine they applied to the cells. They we

.1 mM
.5 mM
2.5 mM
5 mM
10 mM

(A mM = millimole or 1/1000th of a mole).

Now, the molar mass of nicotine is 162.23g/mol. This means that 1M of nicotine = 162.23g. Since 1M = 1mol/liter, this means that there would be 162.23g of nicotine in one liter of their solution.

Now here's where I am wondering if Dr. F messed up his calculation. A millimole = .001 M. Thus a millimole of nicotine = .16223g (let's round to .16g). That would be .16g/L.

Now .1 mM of nicotine = 160g x 0.0001 = .016g/L. And so on for the rest of the chart presented in the paper. Here would be the conversions in grams per liter:

.5 = .08g/L
2.5 = .4g/L
5 = .8g/L
10 = 1.6g/L

Now, you are probably thinking, "Yes, but you have grams per liter. We need milligrams per milliliter. Therefore, you would need to move the decimal three places to the right. Hence, .016g/L would equal 16mg/mL. Right?"

Wrong. 0.016g/L = 0.016mg/mL. It's the same. It's something we learn in elementary school called cancellation.

The density of pure nicotine is 1.01g/cm^3. This equates 1:1 with mg/mL. Thus, the density of pure nicotine (undiluted) would be 1.01g/mL or 1010mg/mL.

Dr. F, is claiming that 10 mM =1600mg/mL. This is impossible as that is more nicotine than is possible to fit into one mL, even if it was pure and undiluted. (As I said above, pure nicotine is 1010mg/mL).

I conclude that Dr. F. is wrong when he says they were using 16mg/mL, 80mg/mL, 400mg/mL, 800mg/mL, and especially 1600mg/mL (impossible), etc. He moved the decimal place over when he shouldn't have. Or perhaps I am completely wrong and talking out my behind (I am not a chemist and admit I could be totally confused about molarity and the densities and masses of the chemicals here).

I know we have chemists here. I would like it if an expert would show me the error of my ways, which I fully admit is possible. Again, I am no expert. I'm just a guy who thought that surely these researchers cannot be so silly as to use outrageous amounts of nicotine such as 1600mg/mL!  

Hey all,

I've always vaped a high nic concentration. Probably since I started in somewhat of the early days 6 years ago at least and the equipment sucked so the high nic levels kinda offset the equipment. Vape 30mg.

I recently got an atty with a big airhole so I was able to go sub ohm at like
.5ohm at 20-30 watts at my normal 30mg+ nic. Holy **** - it kicked my ***!!! I had to drank a gallon of water after 1 in a half hits.

Do any of you guys notice such a big difference in nicotine amounts when switching vaping styles. When I mouth to lung I only take in maybe a quarter of the actual vapor that's produced- but I use like 30mg+ of nic. But I really like the throat hit the high nic amounts provide.

What are your experiences ? Am I crazy with having to use 30mg+ for my normal mouth to lung vaping style.


Sent from my iPad using Tapatalk  

Doctors show how vaping damages lungs, as the number of illnesses continues to rise  

I just got done watching a video from Twisted420 who is supposed to be a reputable vape personality.

The video was a review of the 200w Snow Wolf mod box with temperature control. In the video, Twisted420 was vaping it at ~574 F degrees not to mention when he maxed the temp out at ~662 F. Basically boasting about it being the most powerful temp control mod on the market.

From my understanding, Glycerol (VG) decomposes into acrolein at ~535 F (~280 C). Acrolein is an aldehyde that is a decomposition product of glycerol. Acrolien is one of the main connections between cigarettes and lung cancer.

Anybody buying this for high wattage temp control should be aware of this. For even your biggest cloud producing kanthal builds don't heat as high as twisted420 was vaping. So far the people I see using this device in my vape groups are vaping at these very high temps.

Sent from my HTC One M8 Harman/Kardon edition  

So, new research.

techtimes.
com/articles/53617/20150517/flavor-lung-damage-e-cigarette-varieties-more-harmful-others.htm

"The Flavor Of Lung Damage: Some E-Cigarette Varieties May Be More Harmful Than Others : LIFE : Tech Times"


Opinions?
Was there a rebuttal?  

I enjoy vaping in the following way:

1. Mouth to lung
2. Lung to lung
3. Lung to mouth to lung back into mouth through left nostril
4. Mouth to right nostril back to mouth to lung to left nostril
5. Lung to mouth back to lung
6. Lung to lung to lung back to mouth through left nostril out right ear into mouth back to lung (personal fav)
What's your favorite inhale technique?  

Hey guys,

I originally posted this in the hardware specific section but haven't gotten any love so here goes...

I have been off real cigs for a few months now which I'm super happy about, no desire to go back. I kicked the habit with the aspire K1 Ego tanks and since upgraded to Nautilus mini which I enjoy, I'm primarily mouth to lung hitter. In between the two tanks I was sold an Atlantis by a local B&M, the guy said most buy a Nautilus mini then upgrade to Atlantis anyway so he said it would save money. I couldn't really get into it taking lung hits and still really don't enjoy it but am wondering if my technique is off?

I tried 12mg juice in there and it was really rough, I've since dropped my nicotine to 6mg across the board, and tried that in the Atlantis, it gives a harsh mouth and throat feel if I try to lung hit, I also get the same experience if I use 0mg juice. I've tried MtL hits and it doesn't really produce any vapor. Attempting lung hits I've tried all wattages from 15-30W with same results, also I keep the airflow all the way open. I try and inhale deep and quick thinking more airflow might 'dilute' the vapor and make it feel less harsh. Also this is Atlantis1, and I've only tried max or 100%VG juice.

What technique/settings do you guys use and what should it really feel like doing lung hits on this tank? When he sold me the tank I used it once in the shop and it felt very very smooth on the inhale and smooth on the exhale as well as very dense and tasty and pleasant, for the life of me I can't replicate it. Alternatively, is there a tank or RBA/RTA/RDA I can try for MtL hits that will produce that really dense vapor feel?

TIA for your help, I know it probably sounds like a newbie question lol 'how do I use my tank' but I am stuck!  

Because it has a coil? Because it has a tank that contains VG or PG? Because the user expels vapor that looks like smoke ? Because it has a battery? Because the tank holds liquid that contains nicotine? What if the tank does not contain nicotine? Is it still an E-Cig?

These are my burning questions for tonight while watching Modern Marvels on H2 (History Channel 2)

That and I really need to know what exactly constitutes an E-cig. I've been tobacco free, smoke free for almost two years. Vaping exclusively. I'm close to zero nicotine now. Will I still be an E-cig user when I go to zero? Obviously yes, but why ?

I really dig vaping a million times more then I dug smoking. I hated smoking. Just did it for 40 years 'cause I couldn't get off the stinkies til I discovered E-cig (24 mg/ml when I first quit smoking) almost two years ago. Still can't believe I've been smoke free for so long.

Hope you weigh in on the subject of "What constitutes an E-Cig ?"